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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYST2 All Species: 20.91
Human Site: T289 Identified Species: 32.86
UniProt: O95251 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O95251 NP_008998.1 611 70642 T289 K Y M E H R Q T Y G N T R E P
Chimpanzee Pan troglodytes XP_511869 806 91579 T484 K Y M E H R Q T Y G N T R E P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548192 555 64081 D250 E N L T S E Y D L D L F R R A
Cat Felis silvestris
Mouse Mus musculus Q5SVQ0 613 70623 T291 K Y M E H R Q T Y G N T R E P
Rat Rattus norvegicus Q810T5 612 70496 T290 K Y M E H R Q T Y G N T R E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026512 611 70527 T289 K Y M E H R Q T Y G N T R E P
Frog Xenopus laevis NP_001079995 617 71123 Y289 T K E Q K E K Y M E H R Q T H
Zebra Danio Brachydanio rerio NP_997800 568 65560 Y263 L E N I T S D Y D L E L F R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q960X4 541 61216 K236 G D G S Q D G K T P T P R Q S
Honey Bee Apis mellifera XP_392324 916 101344 K581 C E L Q G N E K D R Q P R L T
Nematode Worm Caenorhab. elegans Q9TYU5 458 53125 L153 T S G S T P S L R G S M S M V
Sea Urchin Strong. purpuratus XP_782361 504 58083 C199 K H R T L W G C P L Y H N M T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LXD7 445 51348 R140 V T S L K M T R H Q K R K I D
Baker's Yeast Sacchar. cerevisiae Q08649 445 52594 S140 G I K D E N I S H E D E I K K
Red Bread Mold Neurospora crassa Q7S9B6 506 58788 Q201 Q P S F S R E Q E I E K L R T
Conservation
Percent
Protein Identity: 100 75.8 N.A. 89.3 N.A. 99 99 N.A. N.A. 97.8 93.1 76.4 N.A. 33.7 34 30.9 39.2
Protein Similarity: 100 75.8 N.A. 89.5 N.A. 99 99 N.A. N.A. 98.5 95.9 83.4 N.A. 49.5 48.1 48.6 53.8
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 100 N.A. N.A. 100 0 0 N.A. 6.6 6.6 6.6 6.6
P-Site Similarity: 100 100 N.A. 20 N.A. 100 100 N.A. N.A. 100 26.6 0 N.A. 13.3 26.6 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 36.3 31.9 31.2
Protein Similarity: N.A. N.A. N.A. 50.4 47.6 47.4
P-Site Identity: N.A. N.A. N.A. 0 0 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 33.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % A
% Cys: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 7 0 7 7 7 14 7 7 0 0 0 7 % D
% Glu: 7 14 7 34 7 14 14 0 7 14 14 7 0 34 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 0 7 7 0 0 % F
% Gly: 14 0 14 0 7 0 14 0 0 40 0 0 0 0 0 % G
% His: 0 7 0 0 34 0 0 0 14 0 7 7 0 0 7 % H
% Ile: 0 7 0 7 0 0 7 0 0 7 0 0 7 7 0 % I
% Lys: 40 7 7 0 14 0 7 14 0 0 7 7 7 7 14 % K
% Leu: 7 0 14 7 7 0 0 7 7 14 7 7 7 7 0 % L
% Met: 0 0 34 0 0 7 0 0 7 0 0 7 0 14 0 % M
% Asn: 0 7 7 0 0 14 0 0 0 0 34 0 7 0 0 % N
% Pro: 0 7 0 0 0 7 0 0 7 7 0 14 0 0 34 % P
% Gln: 7 0 0 14 7 0 34 7 0 7 7 0 7 7 0 % Q
% Arg: 0 0 7 0 0 40 0 7 7 7 0 14 54 20 0 % R
% Ser: 0 7 14 14 14 7 7 7 0 0 7 0 7 0 7 % S
% Thr: 14 7 0 14 14 0 7 34 7 0 7 34 0 7 20 % T
% Val: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 34 0 0 0 0 7 14 34 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _